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1.3.1: Diffusion

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Diffusion: net movement of particles from higher to lower concentration (down the concentration gradient); passive (no energy required).

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Occurs in gases and solutions; does not require energy.

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Examples: O₂ and CO₂ across alveoli; urea from cells into blood plasma.

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Factors affecting rate of diffusion:

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Concentration gradient: larger difference → faster diffusion.

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Temperature: higher → particles have more kinetic energy → faster diffusion.

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Surface area of membrane: larger SA → faster diffusion.

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SA:V ratio: large SA:V ratio (e.g. single-celled organisms) → sufficient diffusion to meet needs.

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As organisms grow larger, SA:V ratio decreases → need specialised exchange surfaces (alveoli, villi, gills, leaf surfaces) and transport systems (circulatory system).

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Adaptations of exchange surfaces:

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Large surface area.

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Thin membrane (short diffusion path).

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Efficient blood supply (animals) to maintain the concentration gradient.

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Ventilation (gaseous exchange in animals) to maintain the concentration gradient.

Common exam mistakes

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Movement 'along' or 'across' a concentration gradient is insufficient — always specify direction: particles move from high to low concentration.

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It is particles, molecules, or ions that diffuse — not cells. Never write that cells move.

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In questions about alveoli, use the word diffusion not absorption — gases diffuse across the alveolar wall; 'absorption' implies active uptake and loses marks in this context.

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Alveolar and villi walls are one cell thick — do not write 'thin cell walls' (a plant structure term) or 'the alveoli have a thin membrane' (the cell membrane is not the same as the wall). The wall is a layer of cells.

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The moist lining of alveoli is not an adaptation for gas exchange — it is a consequence of evaporation from cells, not a feature that increases the rate of diffusion. Do not include it as an adaptation.

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Mitochondria are found in the epithelial cells of the villi, not in the villi themselves — phrase this carefully in extended answers.

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When calculating SA:V, divide surface area by volume — do not give both values as a raw ratio without dividing.

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