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2.2.2: The heart and blood vessels

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Double circulatory system: right side pumps blood to lungs; left side pumps blood to body.

Blood flow through heart:

Vena cavaright atriumright ventriclepulmonary artery (deoxygenated) → lungs.

Lungs → pulmonary vein (oxygenated) → left atriumleft ventricleaorta → body.

Left ventricle has thicker, more muscular walls (pumps blood further to body at higher pressure).

Pacemaker: group of cells in right atrium; sets the natural resting heart rate; artificial pacemakers correct irregular heartbeat.

Arteries: thick walls (muscle and elastic fibres); small lumen; carry blood away from heart at high pressure; no valves.

Veins: thin walls; large lumen; carry blood to heart at low pressure; have valves to prevent backflow.

Capillaries: walls one cell thick; huge surface area; exchange of O₂, CO₂, glucose, urea between blood and cells.

Alveoli adaptations: large surface area; rich blood supply (capillary network); thin walls (one cell thick) — short diffusion distance for gas exchange.

Common exam mistakes

Pulmonary artery carries deoxygenated blood (right ventricle to lungs); pulmonary vein carries oxygenated blood (lungs to left atrium). Students frequently reverse these.

Coronary arteries supply blood to the heart muscle itself — they do NOT carry blood to the lungs or to the rest of the body.

Blood vessels do NOT have cell walls — that term applies to plants. Use 'muscular wall' or 'fibrous wall'.

When comparing arteries and veins: must make comparative statements (e.g. 'arteries have thicker walls THAN veins') — just describing each separately is not enough.

Veins have valves; arteries do NOT — must state this comparison explicitly.

The moist lining of alveoli is NOT a valid adaptation for gas exchange — examiners do not credit this; focus on large surface area, thin walls, and rich blood supply.

Alveoli have thin walls (one cell thick) — do not say 'thin cell walls' (a plant term) or 'thin membranes'; the correct phrase is 'thin walls' or 'walls one cell thick'.

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