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6.1.8: Sex determination

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Ordinary human body cells contain 23 pairs of chromosomes.

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22 pairs control characteristics only.

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One pair of chromosomes carries the genes that determine sex.

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In females the sex chromosomes are the same: XX.

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In males the sex chromosomes are different: XY.

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Sex inheritance cross: eggs carry X; sperm carry X or Y, giving about a 1:1 ratio of XX female to XY male offspring.

Common exam mistakes

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Females are XX and males are XY; do not swap these.

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Eggs carry an X chromosome; sperm carry either X or Y.

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A sex determination cross gives an expected 1:1 ratio, but this does not guarantee every small family has equal numbers of boys and girls.

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If a question adds a sex condition to an inheritance probability, apply that extra probability rather than using only the Punnett square result.

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