Back to Hub/6 Inheritance, Variation and Evolution/6.3 The development of understanding of genetics and evolution

6.3.7: Resistant bacteria

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Antibiotic-resistant bacteria arise by natural selection.

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Bacteria reproduce very quickly, so they can evolve rapidly.

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A random mutation can make a bacterium resistant to an antibiotic.

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When the antibiotic is used, non-resistant bacteria are killed, but the resistant bacteria survive and reproduce.

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The resistant strain spreads because people are not immune to it and there is no effective treatment.

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MRSA is an example of a bacterium resistant to antibiotics.

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To slow down the development of resistant strains:

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doctors should not over-prescribe antibiotics (e.g. not for viral or non-serious infections)

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patients should finish the whole course so all bacteria are killed and none survive to mutate

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the agricultural use of antibiotics should be restricted.

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Developing new antibiotics is slow and costly, so it is hard to keep up with new resistant strains.

Common exam mistakes

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Resistance arises by random mutation then natural selection — bacteria do not "want", "try" or "decide" to become resistant.

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The antibiotic does not cause the mutation; it selects for bacteria that are already resistant.

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Say resistant bacteria survive and reproduce, passing on the resistance — not that they "get used to" the antibiotic.

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Antibiotics kill bacteria, not viruses; taking them for a cold or flu does nothing and adds to resistance.

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"Finish the course" matters because stopping early leaves surviving bacteria that can multiply into resistant strains.

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Use MRSA as the named example if asked.

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