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5.3.2: Control of blood glucose concentration

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Blood glucose concentration is monitored and controlled by the pancreas.

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If blood glucose is too high, the pancreas produces insulin.

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Insulin causes glucose to move from the blood into cells.

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In liver and muscle cells, excess glucose is converted to glycogen for storage.

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Type 1 diabetes occurs when the pancreas fails to produce sufficient insulin, causing uncontrolled high blood glucose.

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Type 1 diabetes is normally treated with insulin injections.

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Type 2 diabetes occurs when body cells no longer respond to insulin produced by the pancreas.

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Type 2 diabetes is commonly treated with a carbohydrate-controlled diet and exercise; obesity is a risk factor.

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Higher tier: if blood glucose is too low, the pancreas produces glucagon, which causes glycogen to be converted into glucose and released into the blood.

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Insulin and glucagon interact in a negative feedback cycle to control blood glucose levels.

Common exam mistakes

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Do not confuse insulin and glucagon: insulin lowers blood glucose, while glucagon raises it.

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Do not choose a graph time when blood glucose is low if the question asks when insulin would be high.

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Insulin causes glucose to move into cells; answers that only say glucose is taken out of the blood are incomplete.

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Type 1 diabetes is normally treated with insulin injections, not diet alone.

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When comparing diabetes data, compare values directly; quoting two numbers without saying which is higher is not enough.

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